Savings Offer*

Help your eligible patients pay as little as $4 per 30-day fill for brand-name LIPITOR. 

For more information on the Savings Offer, click here.

Terms and Conditions

*Eligibility required. Terms and conditions apply. Full terms and conditions can be found at LIPITOR.com/savings-terms. This Savings Offer will be accepted only at participating pharmacies. This Savings Offer is not health insurance. No membership fees. Maximum savings cap of $1,800 per calendar year. This Savings Offer is not valid for prescriptions that are eligible to be reimbursed, in whole or in part, by Medicaid, Medicare, or other federal or state healthcare programs. This Savings Offer is not valid for prescriptions that are eligible to be reimbursed in whole by private insurance plans or other health or pharmacy benefit programs. Viatris reserves the right to revoke, rescind, or amend this Savings Offer without notice. For help with the LIPITOR Savings Offer, call 1-800-314-7957, visit LIPITOR.com, or write: Viatris, 1000 Mylan Boulevard, Canonsburg, PA 15317.

LIPITOR is a registered trademark of Upjohn Manufacturing Ireland Unlimited Company, a Viatris Company.

LIPI-2022-1412 V3

Savings Offer

Dosing & Administration

  • Dose range: 10 to 80 mg once daily.
  • Recommended start dose: 10 or 20 mg once daily.
  • Patients requiring large LDL-C reduction (>45%) may start at 40 mg once daily.
  • Pediatric patients with HeFH: starting dose: 10 mg once daily; dose range: 10 to 20 mg/day for patients 10 years to 17 years of age.

LIPITOR is available by prescription only in 10 mg,
20 mg, 40 mg, and 80 mg tablets.

LIPITOR is a registered trademark of Upjohn Manufacturing Ireland Unlimited Company, a Viatris Company.

LIPI-2022-1412 V3

Dosing and Administration

Help Keep Rx As Prescribed

To help ensure the brand you prescribe is dispensed as written at the pharmacy, write "Dispense as Written" (DAW)* as appropriate on your next LIPITOR prescription.

*Prescription language and requirements may vary based on your state's law.

LIPITOR is a registered trademark of Upjohn Manufacturing Ireland Unlimited Company, a Viatris Company.

LIPI-2022-1412 V3

Help Keep Rx As Prescribed

Resources

LIPITOR continues to provide resources for patients.

For more information on the resources, click here.

LIPITOR is a registered trademark of Upjohn Manufacturing Ireland Unlimited Company, a Viatris Company.

LIPI-2022-1412 V3

Resources
Scroll for Important Safety Information and Indications
IMPORTANT SAFETY INFORMATION AND INDICATIONS

Contraindications:

  • Acute liver failure or decompensated cirrhosis
  • Hypersensitivity to atorvastatin or any excipients in LIPITOR. Hypersensitivity reactions, including anaphylaxis, angioneurotic edema, erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported

Warnings and Precautions:

  • Myopathy and Rhabdomyolysis: Risk factors include age 65 years or greater, uncontrolled hypothyroidism, renal impairment, concomitant use with certain other drugs, and higher LIPITOR dosage. Discontinue LIPITOR if markedly elevated CK levels occur or myopathy is diagnosed or suspected. Temporarily discontinue LIPITOR in patients experiencing an acute or serious condition at high risk of developing renal failure secondary to rhabdomyolysis. Inform patients of the risk of myopathy and rhabdomyolysis when starting or increasing LIPITOR dosage. Instruct patients to promptly report unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever.
  • Immune-Mediated Necrotizing Myopathy (IMNM): Rare reports of IMNM, an autoimmune myopathy, have been reported with statin use. Discontinue LIPITOR if IMNM is suspected.
  • Hepatic Dysfunction: Increases in serum transaminases have occurred, some persistent. Rare reports of fatal and non-fatal hepatic failure have occurred. Consider testing liver enzymes before initiating therapy and as clinically indicated thereafter. If serious hepatic injury with clinical symptoms and/or hyperbilirubinemia or jaundice occurs, promptly discontinue LIPITOR.
  • Increases in HbA1c and Fasting Serum Glucose Levels: Increases in HbA1c and fasting serum glucose levels have been reported with statins, including LIPITOR.
  • Increased Risk of Hemorrhagic Stroke in Patients on LIPITOR 80 mg with Recent Hemorrhagic Stroke: In a post-hoc analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial where 2365 adult patients, without CHD who had a stroke or TIA within the preceding 6 months, were treated with LIPITOR 80 mg, a higher incidence of hemorrhagic stroke was seen in the LIPITOR 80 mg group compared to placebo (55, 2.3% LIPITOR vs. 33, 1.4% placebo; HR: 1.68, 95% CI: 1.09, 2.59; p=0.0168). The incidence of fatal hemorrhagic stroke was similar across treatment groups (17 vs. 18 for the atorvastatin and placebo groups, respectively). The incidence of non-fatal hemorrhagic stroke was significantly higher in the LIPITOR group (38, 1.6%) as compared to the placebo group (16, 0.7%). Some baseline characteristics, including hemorrhagic and lacunar stroke on study entry, were associated with a higher incidence of hemorrhagic stroke in the LIPITOR group. Consider the risk/benefit of use of LIPITOR 80 mg in patients with recent hemorrhagic stroke.

Adverse Reactions:

The most common adverse reactions (incidence ≥5%) are nasopharyngitis, arthralgia, diarrhea, pain in extremity, and urinary tract infection.

Drug Interactions:

  • Drug Interactions that may Increase the Risk of Myopathy and Rhabdomyolysis with LIPITOR: LIPITOR is a substrate of CYP3A4 and transporters (e.g., OATP1B1/1B3, P-gp, or BCRP). LIPITOR plasma levels can be significantly increased with concomitant administration of inhibitors of CYP3A4 and transporters. See full prescribing information for details regarding concomitant use of LIPITOR with other drugs or grapefruit juice that increase the risk of myopathy and rhabdomyolysis.
  • Drug Interactions that may Decrease Exposure to LIPITOR: Rifampin may reduce atorvastatin plasma concentrations. Administer simultaneously with LIPITOR.
  • LIPITOR Effects on Other Drugs:
    • Oral Contraceptives: May increase plasma levels of norethindrone and ethinyl estradiol; consider this effect when selecting an oral contraceptive.
    • Digoxin: May increase digoxin plasma levels; monitor patients appropriately.

Special Populations:

  • Pregnancy: May cause fetal harm.
  • Lactation: Breastfeeding not recommended during treatment with LIPITOR.

Indications

LIPITOR is an HMG-CoA reductase inhibitor (statin) indicated:

  • To reduce the risk of:
    • Myocardial infarction (MI), stroke, revascularization procedures, and angina in adults with multiple risk factors for coronary heart disease (CHD) but without clinically evident CHD.
    • MI and stroke in adults with type 2 diabetes mellitus with multiple risk factors for CHD but without clinically evident CHD.
    • Non-fatal MI, fatal and non-fatal stroke, revascularization procedures, hospitalization for congestive heart failure, and angina in adults with clinically evident CHD.
  • As an adjunct to diet to reduce low-density lipoprotein (LDL-C) in:
    • Adults with primary hyperlipidemia.
    • Adults and pediatric patients aged 10 years and older with heterozygous familial hypercholesterolemia (HeFH).
  • As an adjunct to other LDL-C-lowering therapies to reduce LDL-C in adults and pediatric patients aged 10 years and older with homozygous familial hypercholesterolemia.
  • As an adjunct to diet for the treatment of adults with:
    • Primary dysbetalipoproteinemia.
    • Hypertriglyceridemia.

LIPITOR is available by prescription only in 10 mg, 20 mg, 40 mg, and 80 mg tablets.

Please see Full Prescribing Information and Patient Information.

IMPORTANT SAFETY INFORMATION AND INDICATIONS

See more See Less
LIPITOR® (atorvastatin calcium) tablets are contraindicated in patients with a known hypersensitivity to any component of this product

Contraindications:

  • Acute liver failure or decompensated cirrhosis
  • Hypersensitivity to atorvastatin or any excipients in LIPITOR. Hypersensitivity reactions, including anaphylaxis, angioneurotic edema, erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported

Warnings and Precautions:

  • Myopathy and Rhabdomyolysis: Risk factors include age 65 years or greater, uncontrolled hypothyroidism, renal impairment, concomitant use with certain other drugs, and higher LIPITOR dosage. Discontinue LIPITOR if markedly elevated CK levels occur or myopathy is diagnosed or suspected. Temporarily discontinue LIPITOR in patients experiencing an acute or serious condition at high risk of developing renal failure secondary to rhabdomyolysis. Inform patients of the risk of myopathy and rhabdomyolysis when starting or increasing LIPITOR dosage. Instruct patients to promptly report unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever.
  • Immune-Mediated Necrotizing Myopathy (IMNM): Rare reports of IMNM, an autoimmune myopathy, have been reported with statin use. Discontinue LIPITOR if IMNM is suspected.
  • Hepatic Dysfunction: Increases in serum transaminases have occurred, some persistent. Rare reports of fatal and non-fatal hepatic failure have occurred. Consider testing liver enzymes before initiating therapy and as clinically indicated thereafter. If serious hepatic injury with clinical symptoms and/or hyperbilirubinemia or jaundice occurs, promptly discontinue LIPITOR.
  • Increases in HbA1c and Fasting Serum Glucose Levels: Increases in HbA1c and fasting serum glucose levels have been reported with statins, including LIPITOR.
  • Increased Risk of Hemorrhagic Stroke in Patients on LIPITOR 80 mg with Recent Hemorrhagic Stroke: In a post-hoc analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial where 2365 adult patients, without CHD who had a stroke or TIA within the preceding 6 months, were treated with LIPITOR 80 mg, a higher incidence of hemorrhagic stroke was seen in the LIPITOR 80 mg group compared to placebo (55, 2.3% LIPITOR vs. 33, 1.4% placebo; HR: 1.68, 95% CI: 1.09, 2.59; p=0.0168). The incidence of fatal hemorrhagic stroke was similar across treatment groups (17 vs. 18 for the atorvastatin and placebo groups, respectively). The incidence of non-fatal hemorrhagic stroke was significantly higher in the LIPITOR group (38, 1.6%) as compared to the placebo group (16, 0.7%). Some baseline characteristics, including hemorrhagic and lacunar stroke on study entry, were associated with a higher incidence of hemorrhagic stroke in the LIPITOR group. Consider the risk/benefit of use of LIPITOR 80 mg in patients with recent hemorrhagic stroke.

Adverse Reactions:

The most common adverse reactions (incidence ≥5%) are nasopharyngitis, arthralgia, diarrhea, pain in extremity, and urinary tract infection.

Drug Interactions:

  • Drug Interactions that may Increase the Risk of Myopathy and Rhabdomyolysis with LIPITOR: LIPITOR is a substrate of CYP3A4 and transporters (e.g., OATP1B1/1B3, P-gp, or BCRP). LIPITOR plasma levels can be significantly increased with concomitant administration of inhibitors of CYP3A4 and transporters. See full prescribing information for details regarding concomitant use of LIPITOR with other drugs or grapefruit juice that increase the risk of myopathy and rhabdomyolysis.
  • Drug Interactions that may Decrease Exposure to LIPITOR: Rifampin may reduce atorvastatin plasma concentrations. Administer simultaneously with LIPITOR.
  • LIPITOR Effects on Other Drugs:
    • Oral Contraceptives: May increase plasma levels of norethindrone and ethinyl estradiol; consider this effect when selecting an oral contraceptive.
    • Digoxin: May increase digoxin plasma levels; monitor patients appropriately.

Special Populations:

  • Pregnancy: May cause fetal harm.
  • Lactation: Breastfeeding not recommended during treatment with LIPITOR.

Indications

LIPITOR is an HMG-CoA reductase inhibitor (statin) indicated:

  • To reduce the risk of:
    • Myocardial infarction (MI), stroke, revascularization procedures, and angina in adults with multiple risk factors for coronary heart disease (CHD) but without clinically evident CHD.
    • MI and stroke in adults with type 2 diabetes mellitus with multiple risk factors for CHD but without clinically evident CHD.
    • Non-fatal MI, fatal and non-fatal stroke, revascularization procedures, hospitalization for congestive heart failure, and angina in adults with clinically evident CHD.
  • As an adjunct to diet to reduce low-density lipoprotein (LDL-C) in:
    • Adults with primary hyperlipidemia.
    • Adults and pediatric patients aged 10 years and older with heterozygous familial hypercholesterolemia (HeFH).
  • As an adjunct to other LDL-C-lowering therapies to reduce LDL-C in adults and pediatric patients aged 10 years and older with homozygous familial hypercholesterolemia.
  • As an adjunct to diet for the treatment of adults with:
    • Primary dysbetalipoproteinemia.
    • Hypertriglyceridemia.

LIPITOR is available by prescription only in 10 mg, 20 mg, 40 mg, and 80 mg tablets.

Please see Full Prescribing Information and Patient Information.